Michele Renee Velez Mattiace passed-away peacefully at the Mercy House on June 26, 2021 at the age of 52 after a long and courageous fight with heart disease. She was a very loving and devoted mother to Nestor, Ceferino, Sydney, and Lena. Michele was proceeded in death by her younger sister Darlene and her father Michael. She is survived by her husband Nestor Senior and her four children, her mother Marianne, and three brothers Dean (Susan), Dirk (Dawn), and Darin. Michele was a loving aunt to many loving nieces and nephews. After graduating from high school, Michele attended Stony Brook University where she earned her Nursing Degree. Michele also enjoyed traveling. She traveled frequently to Puerto Rico to visit her father where she met her husband, Nestor Velez. Michele was an avid photographer where she had a knack for capturing many of life’s adventures in black and white photos. Michele loved spending time with her family. There are many fond memories at home, school activities, and outdoor parks, and beaches. Michele cared for many family pets and one of her favorites was her Boxer Roxy who helped her through many difficult times. The family will be hosting a celebration of life in Michele’s memory on Saturday July 17, 2021. In lieu of flowers or cards, please consider making a donation to American Heart Association or The Mercy House of Endicott.